Haku
Viitteet 1-6 / 6
Multimodal approach to the evaluation of diffuse neuroinflammation in multiple sclerosis using positron emission tomography and diffusion tensor imaging
(Åbo Akademi, 2018)
Neuroinflammation, neurodegeneration and demyelination of brain, spinal cord and optic nerves are attributed to multiple sclerosis (MS) pathogenesis. Conventional magnetic resonance imaging (MRI) is mainly used for evaluation ...
Synthesis of CuS@MSN@SpAcDex for Tacrolimus delivery to treat End Stage Renal Disease
(2021)
The treatment of End stage renal disease (ESRD) is kidney transplantation. In order to keep the transplanted kidney safe in the patient’s body, it is necessary to kill the patient’s immune cells present in the endothelial ...
Polyacrylamide Stiffness-gradient Hydrogels : A 2D Culture System to Study Cell Mechano-responsiveness to Substrate Stiffness
(Åbo Akademi, 2019)
Stiffness of the extracellular matrix (ECM) has emerged as a prominent mechanical cue that influences cell behaviour and tissue homeostasis. Importantly, there is growing evidence suggesting that a prolonged dysregulation ...
Identification of glycosylations affected by androgen-regulated process on the surface of extracellular vesicles derived from PCa cell lines
(Åbo Akademi, 2019)
Introduction: Prostate cancer (PCa) is one of the leading death-causing cancers in males. Lack of sensitivity of the current diagnostic approach created an opportunity for a new diagnostic method. Altered glycosylation is ...
Fluorescence imaging of Drosophila melanogaster tracheal system : investigating the morphology of LUBEL mutant flies
(Åbo Akademi, 2020)
Ubiquitination is a post-translational modification that is a key regulator in many pathways in the cell. Mutant LUBEL (lubelMi), linear ubiquitin E3 ligase, flies are unable to form methionine 1 (M1) linked ubiquitin ...
Intracellular Delivery OF CRISPR/Cas9 Plasmid With Zif-8 Nanocarrier to Liver Cancer Cells
(2023)
Hepatocellular carcinomas are the fifth most common cancers with poor prognosis, inefficient drug therapy, and severe side effects. C-Myc regulates up to 20 % of all human genes. C-Myc overexpression is involved in 70 % ...