3111 Biolääketieteet
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Folate receptor beta as an imaging target for inflammatory bowel disease
(2024)In recent years, the global prevalence of inflammatory bowel disease (IBD) has risen significantly, posing substantial challenges to public health. Detecting and monitoring IBD, crucial for effective management, has prompted ... -
Machine learning base tissue probability attenuation correction for neurological PET/MR
(2024)Positron Emission Tomography - Magnetic Resonance Imaging (PET-MR) is a promising imaging modality for neurological disorders, offering valuable insights into brain function and structure simultaneously. However, accurate ... -
Intracellular Delivery OF CRISPR/Cas9 Plasmid With Zif-8 Nanocarrier to Liver Cancer Cells
(2023)Hepatocellular carcinomas are the fifth most common cancers with poor prognosis, inefficient drug therapy, and severe side effects. C-Myc regulates up to 20 % of all human genes. C-Myc overexpression is involved in 70 % ... -
Synthesis of CuS@MSN@SpAcDex for Tacrolimus delivery to treat End Stage Renal Disease
(2021)The treatment of End stage renal disease (ESRD) is kidney transplantation. In order to keep the transplanted kidney safe in the patient’s body, it is necessary to kill the patient’s immune cells present in the endothelial ... -
Targeted Sequence Delivery Platform with ROS-Response for the Treatment of Osteoarthritis
(2021)Arthritis is a common problem affecting elderly people today. One specific form of arthritis is osteoarthritis, caused by lubrication deficiency at the joint surface. Due to genetics, aging, stress factors, or accidents, ... -
Fluorescence imaging of Drosophila melanogaster tracheal system : investigating the morphology of LUBEL mutant flies
(Åbo Akademi, 2020)Ubiquitination is a post-translational modification that is a key regulator in many pathways in the cell. Mutant LUBEL (lubelMi), linear ubiquitin E3 ligase, flies are unable to form methionine 1 (M1) linked ubiquitin ... -
Polyacrylamide Stiffness-gradient Hydrogels : A 2D Culture System to Study Cell Mechano-responsiveness to Substrate Stiffness
(Åbo Akademi, 2019)Stiffness of the extracellular matrix (ECM) has emerged as a prominent mechanical cue that influences cell behaviour and tissue homeostasis. Importantly, there is growing evidence suggesting that a prolonged dysregulation ... -
Developing a High-Throughput System for monitoring Zebrafish Behaviour
(Åbo Akademi, 2019)The aim of this thesis project was to develop a high-throughput (HT) system for recording the behaviour of zebrafish larvae in response to light stimuli. This was achieved by using a compatible camera, Raspberry Pi Camera ... -
Keratins in β-cells of the pancreas and their role for mitochondria and insulin vesicles
(Åbo Akademi, 2019) -
3D Bioprinting of Nanoparticle Incorporated Cell-Laden Bioink for Muscle Tissue Engineering
(Åbo Akademi, 2019)Embargo until 10.6.2022 -
Colonocyte Keratins are upregulated in hypoxia and affects nuclear translocation of HIF-1a
(Åbo Akademi, 2019)The cytoskeleton is divided into three types: microtubules, microfilaments and intermediate filaments (IFs). IFs are further divided into 6 different types. First two types of IFs are type I and type II keratins. Keratins ...Embargo until 24.5.2020 -
Identification of glycosylations affected by androgen-regulated process on the surface of extracellular vesicles derived from PCa cell lines
(Åbo Akademi, 2019)Introduction: Prostate cancer (PCa) is one of the leading death-causing cancers in males. Lack of sensitivity of the current diagnostic approach created an opportunity for a new diagnostic method. Altered glycosylation is ... -
Multimodal approach to the evaluation of diffuse neuroinflammation in multiple sclerosis using positron emission tomography and diffusion tensor imaging
(Åbo Akademi, 2018)Neuroinflammation, neurodegeneration and demyelination of brain, spinal cord and optic nerves are attributed to multiple sclerosis (MS) pathogenesis. Conventional magnetic resonance imaging (MRI) is mainly used for evaluation ...Embargo 29.10.2019 asti
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