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Phenotypic impact of keratin 8/18 downregulation in colonic in vitro 3D cultures
(2022)
The second deadliest and third most common type of cancer is colorectal cancer (CRC). The disease mechanism is to a large extent unknown and the number of cases is on the rise in westernized countries. Interestingly, ...
Keratin 8 i regleringen av ER-stressresponsen i β-celler
(2020)
Under utvecklingen av diabetes, förlorar β-cellerna sin förmåga att utsöndra insulin, minskar i cellmassa och slutligen genomgår β-celldöd. Det är dock inte känt vilka genetiska faktorer som gör att β-cellerna i diabetiska ...
Regulation of keratins in colonocytes during inflammatory signaling
(2023)
The colon is part of the gastrointestinal tract, with the main function of absorbing water, moving and storing fecal material as well as inhabiting micro-organisms. Keratins are intermediate filament proteins important for ...