Selaus julkaisuajan mukaan kokoelmassa 1182 Biokemia, solu- ja molekyylibiologia
Viitteet 1-20 / 73
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Regulation of Death Receptor Responses by Hyperthermia
(Åbo Akademi - Åbo Akademi University, 01.06.2007)Cells need a variety of responses to protect themselves against stresses caused by changes in the environment. Likewise, a complex apoptotic machinery is necessary for elimination of cells that are no longer needed in the ... -
Assessment of endocrine disrupting activities in the aquatic environment
(Åbo Akademi - Åbo Akademi University, 16.01.2009)Hormonstörande ämnen är syntetiska eller naturliga ämnen som stör organismers hormonsystem och bidrar till könsförvirring och sterilitet. Sådana ämnen kommer i ökande takt ut i vattenmiljön genom rester av läkemedel, ... -
Biogeochemistry in acid sulphate soil landscapes and small urban centres in Western Finland
(Åbo Akademi - Åbo Akademi University, 29.01.2010)The overall purpose of this thesis was to increase the knowledge on the biogeochemistry of rural acid sulphate (AS) soil environments and urban forest ecosystems near small towns in Western Finland. In addition, the potential ... -
Dynamic interplay between the intermediate filament protein nestin and Cyclin-dependent kinase 5
(Åbo Akademi - Åbo Akademi University, 29.10.2010) -
Fast LC-MS detection of cyanobacteria peptide hepatotoxins – method development for determination of total contamination levels in biological materials
(Åbo Akademi - Åbo Akademi University, 05.11.2010) -
Lethal weapons : novel approaches for receptor-targeted cancer cell elimination
(Åbo Akademi - Åbo Akademi University, 17.12.2010)The currently used forms of cancer therapy are associated with drug resistance and toxicity to healthy tissues. Thus, more efficient methods are needed for cancer-specific induction of growth arrest and programmed cell ... -
Role and regulatory mechanisms of heat shock factor 2
(Åbo Akademi - Åbo Akademi University, 04.11.2011)Protein homeostasis is essential for cells to prosper and survive. Various forms of stress, such as elevated temperatures, oxidative stress, heavy metals or bacterial infections cause protein damage, which might lead to ... -
Removal of cyanobacterial toxins by strains of probiotic bacteria
(Åbo Akademi - Åbo Akademi University, 21.12.2011) -
Contributions to risk assessment of microcystins, cyanobacterial toxins : development of immunoanalysis and characterization of microcystin variants
(Åbo Akademi - Åbo Akademi University, 15.06.2012) -
TR(i)P, TR(i)P, hooray : new functions for TRPC2 and TRPC3
(Åbo Akademi - Åbo Akademi University, 14.09.2012) -
Effects of methylation and hydroxylation of sphingomyelins on their biophysical properties and interactions with cholesterol
(Åbo Akademi - Åbo Akademi University, 28.09.2012) -
Role of the canonical transient receptor potential channel 2 (TRPC2) in thyroid cell function
(Åbo Akademi - Åbo Akademi University, 08.02.2013)- -
JNK, a versatile regulator of kinesin-1 transport and cytoskeleton dynamics
(Åbo Akademi - Åbo Akademi University, 11.02.2013)C-Jun N-terminal kinase (JNK) is traditionally recognized as a crucial factor in stress response and inducer of apoptosis upon various stimulations. Three isoforms build the JNK subfamily of MAPK; generally expressed JNK1 ... -
Glycolipid and ceramide transfer proteins : important determinants for their function
(Åbo Akademi - Åbo Akademi University, 12.04.2013)- -
Prediction of 3D structure and ligand-binding properties : ABC transporters and flavodiiron proteins from Synechocystis sp. strain PCC 6803
(Åbo Akademi - Åbo Akademi University, 24.05.2013)Cyanobacteria are unicellular, non-nitrogen-fixing prokaryotes, which perform photosynthesis similarly as higher plants. The cyanobacterium Synechocystis sp. strain PCC 6803 is used as a model organism in photosynthesis ... -
Cellular responses to stress and kinase signaling activation : apoptosis and differentiation
(Åbo Akademi - Åbo Akademi University, 13.08.2013)Stress signals are often sensed by membrane-bound proteins which translate signals into the chemical modification of molecules, most notably protein kinases. These kinases, in turn, transmit the decoded message through a ... -
Regulation of cell fate by c-FLIP phosphorylation
(Åbo Akademi - Åbo Akademi University, 13.12.2013)Programmed cell death is an important physiological cellular process that maintains homeostasis and protects multicellular organisms from diseases. Apoptosis is the principal mode of cell death, which eliminates unwanted ... -
Muscarinic toxins : characterization of adrenoceptor binding and applicability of membrane anchoring via glycosylphosphatidylinositol tail
(Åbo Akademi - Åbo Akademi University, 31.01.2014)Adrenoceptors (ARs), G-protein coupled receptors (GPCRs) at the plasma membrane, respond to endogenous catecholamines noradrenaline and adrenaline. These receptors mediate several important physiological functions being ... -
Membrane properties of structurally modified ceramides : effects on lipid lateral distribution and sphingomyelin-interactions in artificial bilayer membranes
(Åbo Akademi - Åbo Akademi University, 14.03.2014)Ceramides comprise a class of sphingolipids that exist only in small amounts in cellular membranes, but which have been associated with important roles in cellular signaling processes. The influences that ceramides have ... -
Selective inhibition of human tankyrases
(Åbo Akademi - Åbo Akademi University, 28.03.2014)Tankyrases belong to the Diphtheria toxin-like ADP-ribosyltransferase (ARTD) enzyme superfamily, also known as poly(ADP-ribose) polymerases (PARPs). They catalyze a covalent post-translational modification reaction where ...
